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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
7.58
Human Site:
T1481
Identified Species:
13.89
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
T1481
P
S
L
P
A
L
L
T
Q
P
R
K
P
T
H
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
T1484
P
S
L
P
A
L
L
T
Q
P
R
K
P
T
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
T1460
S
P
P
A
T
P
L
T
Q
P
R
K
S
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
R1484
E
S
S
Q
K
P
P
R
R
H
S
R
P
Q
G
Rat
Rattus norvegicus
O54889
1716
194174
R1484
S
S
Q
N
P
P
C
R
H
S
R
P
Q
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
E1170
G
D
V
A
V
H
G
E
A
V
V
C
V
T
P
Frog
Xenopus laevis
NP_001082182
1730
195193
P1495
V
E
S
P
T
A
V
P
G
T
P
S
Q
K
L
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
E1463
S
Q
Q
R
V
N
S
E
Q
P
K
G
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
D1418
D
D
E
E
K
G
Q
D
G
N
D
N
D
G
D
Honey Bee
Apis mellifera
XP_001121092
1665
190473
E1425
D
E
D
D
D
D
I
E
K
E
K
S
E
Y
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
T1487
L
D
G
E
D
Q
T
T
E
P
L
L
V
N
S
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
K1507
E
S
Q
S
S
S
R
K
K
K
K
R
Q
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
N1437
K
S
I
V
E
A
N
N
N
M
N
K
V
Q
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
46.6
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
13.3
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
N.A.
46.6
N.A.
26.6
13.3
N.A.
N.A.
13.3
13.3
26.6
N.A.
0
20
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
16
0
0
8
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
16
24
8
8
16
8
0
8
0
0
8
0
8
0
8
% D
% Glu:
16
16
8
16
8
0
0
24
8
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
8
8
0
16
0
0
8
0
16
8
% G
% His:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
16
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
16
0
0
8
16
8
24
31
0
8
0
% K
% Leu:
8
0
16
0
0
16
24
0
0
0
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
8
8
8
8
8
0
8
0
% N
% Pro:
16
8
8
24
8
24
8
8
0
39
8
8
24
0
8
% P
% Gln:
0
8
24
8
0
8
8
0
31
0
0
0
24
16
16
% Q
% Arg:
0
0
0
8
0
0
8
16
8
0
31
16
0
0
8
% R
% Ser:
24
47
16
8
8
8
8
0
0
8
8
16
16
8
8
% S
% Thr:
0
0
0
0
16
0
8
31
0
8
0
0
0
31
0
% T
% Val:
8
0
8
8
16
0
8
0
0
8
8
0
24
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _